We choose appropriate fillers following skin analysis and medical history, and based upon whether we are attempting to soften facial creases and lines, restore/create volume and fullness, or smooth uneven texture caused by scarring. Today we have filler choices that can be very temporary, such as human-based collagen, and others that can last from one to several years, including highly cross-linked hyaluronic acid, calcium hydroxylapatite, and polymethylmethacrylate. Often, these fillers are layered to improve results. There are many new fillers on the horizon, so the options will be even greater soon. The placement and choice of filler to be used should always be individualized and your injector should be knowledgeable, experienced, and have a good eye for balance and beauty.